Small bowel (small intestine)
Benign tumors and tumor-like conditions
Ischemia

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 19 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Ischemia[TI] small bowel[TI]

Cite this page: Gulwani, H. Ischemia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelischemia.html. Accessed June 19th, 2018.
Definition / general
  • Mucosal damage (initially) due to vascular occlusion or reduced blood flow associated with shunting
  • Usually not due to atherosclerosis because of widely anastomosing blood supply
  • Damage varies from none to hemorrhagic infarction
  • Also ulceration, mucosal plaque, strictures
  • Grossing bowel specimens with possible ischemia: dissect blood vessels and submit several sections to detect inflammation and thrombosis
Gross images

Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Early: lamina propria hemorrhage, superficial epithelial necrosis, preservation of deep crypts
  • Later: ulceration with minimal inflammation, villous distortion, pyloric gland metaplasia progressing to full thickness infarct
  • Late: strictures affecting muscularis propria
Microscopic (histologic) images

Images hosted on other servers:

Various images

Differential diagnosis
  • Crohn's disease: marked inflammatory infiltrate, no stricture of muscularis propria, no hemosiderin