Small bowel (small intestine)

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Small bowel (small intestine)

Infectious disorders

Isospora belli

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 17 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Coccidian parasite that infects epithelial cells of small intestine
● Causes chronic diarrhea and acalculous cholecystitis in AIDS patients (Indian J Med Res 2011;134:878)

Life cycle

Diagnosis
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● Cysts in stool, biopsy (H&E or EM)

Case reports
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● 35 year old HIV+ man (Indian J Pathol Microbiol 2010;53:824)

Micro description
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● Cysts present in parasitophorous vacuole in lamina propria (Hum Pathol 2001;32:500)
● Ovoid developmental forms are identified in and beneath epithelial cells near villus tip

Micro images
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Various images

Isospora belli (20-30 µm long by 10-19 µm wide) - immature oocyst (Modified acid fast stain)

Positive stains
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● Giemsa

End of Small bowel (small intestine) > Infectious disorders > Isospora belli

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