Small bowel (small intestine)
Benign tumors and tumor-like conditions
Kayexalate damage

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 19 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Kayexalate damage

Cite this page: Gulwani, H. Kayexalate damage. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelkayexelate.html. Accessed July 18th, 2018.
Definition / general
Case reports
Microscopic (histologic) description
  • Crystals are lightly basophilic with a faint crystalline mosaic pattern, better seen with PAS / Alcian blue
  • Crystals are refractile but not polarizable, luminal and adherent to intact surface epithelium or mixed with inflammatory exudates in patients with ulcer or erosion
Microscopic (histologic) images

Images hosted on other servers:

Various images


Fig. a: kayexalate crystals are variable sizes, all showing a mosaic "cracking" pattern;
patient had severe cardiovascular compromise and received kayexalate for hypokalemia;
bowel was necrotic and ischemic; fig. b: cholestyramine crystals resemble kayexalate but are red;
larger crystals show some mosaic "cracking" but smaller cholestyramine crystals do not