Small bowel (small intestine)
Benign tumors and tumor-like conditions
Kayexalate damage


Topic Completed: 1 August 2012

Revised: 13 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Kayexalate damage

Hanni Gulwani, M.B.B.S.
Page views in 2018: 255
Page views in 2019 to date: 400
Cite this page: Gulwani H. Kayexalate damage. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelkayexelate.html. Accessed November 21st, 2019.
Definition / general
Case reports
Microscopic (histologic) description
  • Crystals are lightly basophilic with a faint crystalline mosaic pattern, better seen with PAS / Alcian blue
  • Crystals are refractile but not polarizable, luminal and adherent to intact surface epithelium or mixed with inflammatory exudates in patients with ulcer or erosion
Microscopic (histologic) images

Images hosted on other servers:

Various images


Fig. a: kayexalate crystals are variable sizes, all showing a mosaic "cracking" pattern;
patient had severe cardiovascular compromise and received kayexalate for hypokalemia;
bowel was necrotic and ischemic; fig. b: cholestyramine crystals resemble kayexalate but are red;
larger crystals show some mosaic "cracking" but smaller cholestyramine crystals do not

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