Small bowel (small intestine)
Lymphoma
General


Topic Completed: 1 August 2012

Revised: 15 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Lymphoma[TI] small bowel[TI]

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Lymphoma - general. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowellymphomageneral.html. Accessed July 20th, 2019.
Definition / general
  • One of most common malignant tumors in small bowel
  • GI tract is most common site of primary extranodal lymphoma but also a site of secondary disease in 10% with non-Hodgkin lymphoma at presentation
  • Usually solitary, 50% have nodal metastases at diagnosis
  • 2 year actuarial survival is 42%
  • If biopsy shows atypical lymphoid proliferation, recommend rebiopsy to obtain fresh tissue for flow cytometry, PCR or gene rearrangement studies
  • 2/3 are B cell, 1/3 are T cell lymphomas
Gross description
  • Diffusely infiltrating mass with garden hose appearance OR bulky tumor mass with ulceration OR polypoid growth pattern
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