Small bowel (small intestine)

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 21 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Lymphoma[TI] small bowel[TI]

Cite this page: Gulwani, H. Lymphoma - general. website. Accessed October 18th, 2018.
Definition / general
  • One of most common malignant tumors in small bowel
  • GI tract is most common site of primary extranodal lymphoma but also a site of secondary disease in 10% with non-Hodgkin lymphoma at presentation
  • Usually solitary, 50% have nodal metastases at diagnosis
  • 2 year actuarial survival is 42%
  • If biopsy shows atypical lymphoid proliferation, recommend rebiopsy to obtain fresh tissue for flow cytometry, PCR or gene rearrangement studies
  • 2/3 are B cell, 1/3 are T cell lymphomas
Gross description
  • Diffusely infiltrating mass with garden hose appearance OR bulky tumor mass with ulceration OR polypoid growth pattern