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Small bowel (small intestine)

Lymphoma

Lymphoma-general


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● One of most common malignant tumors in small bowel
● GI tract is most common site of primary extranodal lymphoma, but also a site of secondary disease in 10% with non-Hodgkin’s lymphoma at presentation
● Usually solitary, 50% have nodal metastases at diagnosis
● 2 year actuarial survival is 42%
● If biopsy shows atypical lymphoid proliferation, recommend rebiopsy to obtain fresh tissue for flow cytometry, PCR or gene rearrangement studies
● 2/3 are B cell, 1/3 are T cell lymphomas

Gross description
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● Diffusely infiltrating mass with garden hose appearance OR bulky tumor mass with ulceration OR polypoid growth pattern

Additional references
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Int J Hematol 2008;87:375, J Int Med Res 2007;35:406, Histopathology 2003;43:135

End of Small bowel (small intestine) > Lymphoma > Lymphoma-general


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