Small bowel (small intestine)

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Small bowel (small intestine)

Infectious disorders

Mycobacteria

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 18 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

See also Tuberculosis

General
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● Aerobic and nonmotile bacteria without endospores or capsules that typically cause small bowel disease only in immunosuppressed or HIV+, usually as part of disseminated infection

Case reports
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● 31 year old woman with HIV and upper GI bleeding (Clin Infect Dis 2009;48:321, answer to quiz)

Micro description
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● Foamy macrophages fill lamina propria
● Usually patchy, no fat vacuoles

Micro images
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Disseminated Mycobacterium avium intracellulare complex (MAC) with nodular infiltration of duodenum

Acid-fast stain: site unspecified

Positive stains
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● PAS (faintly positive bacillary forms), acid-fast stains

Differential diagnosis
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● Whipple’s disease

End of Small bowel (small intestine) > Infectious disorders > Mycobacteria

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