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Small bowel (small intestine)

Benign tumors and tumor-like conditions

Myxoma


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Extremely rare in small intestine
● May be part of Carney complex (familial myxoma syndrome), an autosomal dominant syndrome with 17q2 mutation and cardiac and cutaneous myxomas, lentigines, myxoid fibromas of the breast, pituitary adenomas, primary adrenocortical micronodular hyperplasia with Cushing syndrome, psammomatous melanotic schwannoma, testicular large cell calcifying Sertoli cell tumor (Medicine (Baltimore) 1985;64:270)

Case reports
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● 47 year old woman with simultaneous cardiac and small bowel myxoma (Arch Pathol Lab Med 2003;127:481)

Gross description
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● Intraluminal, pedunculated, firm round nodule with smooth and ulcerated mucosal surface, myxoid and gelatinous cut surface

Micro description
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● Bland, stellate stromal cells and small, mature capillaries widely separated by myxoid material
● Scattered lymphocytes and plasma cells
● No mitotic activity, no atypia

Micro images
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Various images

Positive stains
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● Vimentin

Negative stains
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● CD117/KIT, CD31, smooth muscle actin, S100

End of Small bowel (small intestine) > Benign tumors and tumor-like conditions > Myxoma


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