Small bowel (small intestine)
Inflammatory disorders
Sarcoidosis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 13 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis small bowel

Cite this page: Gulwani, H. Sarcoidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelsarcoidosis.html. Accessed April 21st, 2018.
Definition / general
  • Multisystemic disorder of unknown cause characterized by noncaseating granulomas in involved organs (Orphanet J Rare Dis 2007;2:46); usually does NOT involve the small bowel (QJM 2010;103:60)
  • Must rule out Crohn's disease before making this diagnosis
  • Presents with malabsorption, protein losing enteropathy and lymphangiectasia secondary to lymphatic obstruction
Case reports
Clinical images

Images hosted on other servers:

Gastroscopy shows duodenal granulomatous involvement

Microscopic (histologic) description
  • Compact bland noncaseating granulomas that involve bowel wall and regional nodes
  • Must rule out Crohn's disease
  • Negative stains / PCR for fungi, AFB
Microscopic (histologic) images

Images hosted on other servers:

Various images