Small bowel (small intestine)
Inflammatory disorders
Sarcoidosis


Topic Completed: 1 August 2012

Revised: 12 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis small bowel
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Cite this page: Gulwani H. Sarcoidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelsarcoidosis.html. Accessed March 23rd, 2019.
Definition / general
  • Multisystemic disorder of unknown cause characterized by noncaseating granulomas in involved organs (Orphanet J Rare Dis 2007;2:46); usually does NOT involve the small bowel (QJM 2010;103:60)
  • Must rule out Crohn's disease before making this diagnosis
  • Presents with malabsorption, protein losing enteropathy and lymphangiectasia secondary to lymphatic obstruction
Case reports
Clinical images

Images hosted on other servers:

Gastroscopy shows duodenal granulomatous involvement

Microscopic (histologic) description
  • Compact bland noncaseating granulomas that involve bowel wall and regional nodes
  • Must rule out Crohn's disease
  • Negative stains / PCR for fungi, AFB
Microscopic (histologic) images

Images hosted on other servers:

Various images

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