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Small bowel (small intestine)
Obstruction
Scleroderma
Reviewer: Hanni Gulwani, M.D. (see Reviewers
page)
Revised: 18 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
General
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● Also called progressive systemic sclerosis
● GI manifestations in 50-90% (Rheumatology (Oxford) 2009;48:iii36)
● May cause malabsorption syndrome (related to bacterial overgrowth), intestinal pseudo-obstruction (Presse Med 2006;35:1952)
Micro description
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● Dense fibrosis replacing entire muscularis propria or accentuated in inner layer
● No vacuolar change
End of Small bowel (small intestine) > Obstruction > Scleroderma
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