Small bowel (small intestine)
Small cell carcinoma

Topic Completed: 1 August 2012

Revised: 15 March 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Small cell carcinoma[TIAB] small bowel

Hanni Gulwani, M.B.B.S.
Page views in 2019: 214
Page views in 2020 to date: 36
Cite this page: Gulwani H. Small cell carcinoma. website. Accessed February 18th, 2020.
Definition / general
  • Rare, in few cases reported, prognosis better than for small cell lung tumors
Microscopic (histologic) description
  • Sheets and nests of small, round cells with scanty cytoplasm, hyperchromatic nuclei, stippled chromatin, indistinct nucleoli, numerous mitotic figures and apoptotic cells
  • Foci of necrosis and vascular invasion common
  • Resembles pulmonary tumor
  • Pure or mixed with adenocarcinoma
Microscopic (histologic) images

Images hosted on other servers:

Tumor of proximal ileum; figure 4 is synaptophysin

Positive stains
  • Neuroendocrine markers, CK8, may be TTF1 positive
Electron microscopy description
  • Membrane bound dense core granules
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