Small bowel (small intestine)
Small cell carcinoma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 21 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Small cell carcinoma[TIAB] small bowel

Cite this page: Gulwani, H. Small cell carcinoma. website. Accessed October 16th, 2018.
Definition / general
  • Rare, in few cases reported, prognosis better than for small cell lung tumors
Microscopic (histologic) description
  • Sheets and nests of small, round cells with scanty cytoplasm, hyperchromatic nuclei, stippled chromatin, indistinct nucleoli, numerous mitotic figures and apoptotic cells
  • Foci of necrosis and vascular invasion common
  • Resembles pulmonary tumor
  • Pure or mixed with adenocarcinoma
Microscopic (histologic) images

Images hosted on other servers:

Tumor of proximal ileum; figure 4 is synaptophysin

Positive stains
  • Neuroendocrine markers, CK8, may be TTF1 positive
Electron microscopy description
  • Membrane bound dense core granules