Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Small bowel (small intestine)

Carcinoma

Small cell carcinoma


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 12 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Rare, in few cases reported, prognosis better than for small cell lung tumors

Micro description
=========================================================================

● Sheets and nests of small, round cells with scanty cytoplasm, hyperchromatic nuclei, stippled chromatin, indistinct nucleoli, numerous mitotic figures and apoptotic cells
● Foci of necrosis and vascular invasion common
● Resembles pulmonary tumor
● Pure or mixed with adenocarcinoma

Micro images
=========================================================================



Tumor of proximal ileum; figure 4 is synaptophysin

Positive stains
=========================================================================

● Neuroendocrine markers, CK8, may be TTF1 positive

Electron microscopy description
=========================================================================

● Membrane-bound dense core granules

Additional references
=========================================================================

Arch Pathol Lab Med 2003;127:e357, J Clin Oncol 2004;22:2730, J Clin Pathol 2010;63:620

End of Small bowel (small intestine) > Carcinoma > Small cell carcinoma


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).