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Small bowel (small intestine)


Staging neuroendocrine tumors

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 12 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Click here for staging for ampullary tumors
● See also PubCan

Primary tumor (T)

TX: Primary tumor cannot be assessed
T0: No evidence for primary tumor
T1: Tumor invades lamina propria or submucosa and size 1 cm or less
T2: Tumor invades muscularis propria or size > 1 cm
T3: Tumor invades through the muscularis propria into subserosal tissue without penetration of overlying serosa (jejunal or ileal tumors) or invades pancreas or retroperitoneum (ampullary or duodenal tumors) or into non-peritonealized tissues
T4: Tumor invades visceral peritoneum (serosa) or invades other organs

● For any T, add (m) for multiple tumors

Regional lymph nodes (N)

NX: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Regional lymph node metastasis

● For duodenal tumors, the regional lymph nodes are duodenal, hepatic, pancreaticoduodenal, infrapyloric, gastroduodenal, pyloric, superior mesenteric, pericholedochal nodes
● For ileal and jejunal tumors, the regional lymph nodes are the cecal (for tumors arising in the terminal ileum), superior mesenteric, mesenteric nodes
● Metastases to celiac nodes are considered distant metastases

Distant Metastasis (M)

M0: No distant metastasis
M1: Distant metastasis

Anatomic stage / prognostic groups

Stage I: T1 N0 M0
Stage IIA: T2 N0 M0
Stage IIB: T3 N0 M0
Stage IIIA: T4 N0 M0
Stage IIIB: Any T N1 M0
Stage IV: M1 (any T, any N)

End of Small bowel (small intestine) > Miscellaneous > Staging neuroendocrine tumors

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