Small intestine & ampulla
Infectious disorders
Strongyloides stercoralis

Topic Completed: 1 August 2012

Minor changes: 18 September 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Strongyloides stercoralis[TI] small bowel

Hanni Gulwani, M.B.B.S.
Page views in 2019: 2,246
Page views in 2020 to date: 1,642
Cite this page: Gulwani H. Strongyloides stercoralis. website. Accessed September 29th, 2020.
Definition / general
  • Nematode with complex life cycle that alternates between free living and parasitic cycles, with potential for autoinfection and multiplication within host
Life cycle
  • Larvae burrow into mucosa of duodenum and jejunum, where they mature into adults
  • Females lay eggs, which develop into larvae that pass into stool, where they mature and become infective
  • Infective larvae in soil penetrate intact skin, usually through feet
  • Larvae enter circulatory system, are transported to lungs, enter alveolar spaces, are carried to trachea and pharynx, are swallowed and enter intestinal tract, where process is repeated
  • If larvae become infective before leaving body, they may invade intestinal mucosa or perianal skin, causing autoinfection
Diagrams / tables

Images hosted on other servers:

Life cycle

Clinical features
  • Symptoms: none, diarrhea, malabsorption
  • Severe / fatal infections in immunocompromised, due to worms moving from GI tract into other organs (WormBook 2007:1)
  • Larvae in stool
  • Adult female or eggs in small bowel mucosa, often with eosinophilic or granulomatous inflammation
Case reports
Microscopic (histologic) images

Contributed by Dr. Josehp Christopher Castillo, Institute of Anatomical Pathology Arias Stella, Peru

Small intestine

Case of the Week #133

Various images

Additional references
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