Small bowel (small intestine)
Infectious disorders

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 14 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Tuberculosis[TI] small bowel[TIAB]

Cite this page: Gulwani, H. Tuberculosis. website. Accessed October 20th, 2018.
Definition / general
  • Disease occasionally seen in less developed countries
  • Small intestinal disease may be transmitted via contaminated milk
  • Symptoms: abdominal pain, malabsorption, strictures, perforation, fistula
  • Terminal ileum, cecum, appendix
Gross description
  • Multiple and circumferential ulcers and strictures
Microscopic (histologic) description
  • Confluent granulomas with central necrosis and peripheral lymphocytosis
  • Destruction of muscularis propria, scarring
Microscopic (histologic) images

Images hosted on other servers:

Granulomas in mucosa and submucosa

Images contributed by Dr. Hanni Gulwani:

Ileocecal tuberculosis in 45 year old woman; epithelioid granulomas with Langhans giant cells in lamina propria

Ileocecal tuberculosis and adjoining draining lymph node

Positive stains
Differential diagnosis