Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Small bowel (small intestine)

Infectious disorders

Yersinia


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 17 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Common cause of bacterial enteritis in US, Canada, Australia, Western Europe, Northern Europe (eMedicine)
● Infection due to Y. enterocolitica, Y. pseudotuberculosis, gram negative invasive rods
● Bacteria present in infected milk, pork, water supplies, domestic pets and farm animals
● Causes enterocolitis, acute appendicitis, mesenteric lymphadenitis in children and adolescents
● Pathogenic strains invade small intestinal mucosa via M cells overlying Peyer’s patches, multiply there and within regional nodes, then spreads hematogenously and via lymphatics
● Patients homozygous for Thalassemia major are at risk of Y. enterocolitica, because they have iron overload and the bacteria require iron for growth

Sites
=========================================================================

● Ileum, right colon, appendix

Diagnosis
=========================================================================

● Culture

Case reports
=========================================================================

● 4 year old boy with intussusception due to Y. enterocolitica infection (Arch Pathol Lab Med 2001;125:1486)

Micro description
=========================================================================

● Elongated ulcerations overlying lymphoid hyperplasia
● Also small aphthoid ulcers overlying colonies of gram negative rods and with neutrophils at ulcer base
● Also necrotizing granulomas (particularly with Y. pseudotuberculosis)
● Mesenteric nodes show follicular hyperplasia with variable scattered microabscesses and epithelioid granlomas

Micro images
=========================================================================



Various images

Differential diagnosis
=========================================================================

Crohn’s disease
Mycobacteria
Typhoid fever

End of Small bowel (small intestine) > Infectious disorders > Yersinia


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).