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Soft Tissue Tumors Part 3 - Muscle, Vascular, Nerve, Other
Anaplastic rhabdomyosarcoma
Author: Nat Pernick, M.D, PathologyOutlines.com, Inc.
Revised: 14 July 2009, last major update July 2009
Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.
Terminology
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● In children (but not adults), includes cases previously called pleomorphic rhabdomyosarcoma
● Not a WHO diagnosis
● See also anaplastic variant of embryonal rhabdomyosarcoma
Treatment and prognosis
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● Poor prognosis, particularly if anaplastic cells are aggregated in a clone-like cluster
Micro description
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● Cells have enlarged, pleomorphic, hyperchromatic nuclei
● Atypical polar mitotic figures
Micro images
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Cluster of cells with enlarged, pleomorphic, hyperchromatic nuclei
Additional references
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End of Soft Tissue Tumors Part 3 - Muscle, Vascular, Nerve, Other > Anaplastic rhabdomyosarcoma
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