Soft tissue
Adipose tissue
Hemosiderotic fibrohistiocytic lipomatous lesion

Topic Completed: 1 August 2012

Revised: 20 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Hemosiderotic fibrohistiocytic lipomatous lesion

Vijay Shankar, M.D.
Page views in 2018: 954
Page views in 2019 to date: 822
Cite this page: Shankar V. Hemosiderotic fibrohistiocytic lipomatous lesion. website. Accessed September 18th, 2019.
Definition / general
  • Superficial benign fatty lesion, usually of foot / ankle, with CD34+ spindle cells and abundant hemosiderin
  • Possibly a reactive lesion
  • Not a WHO diagnosis
Case reports
  • Radical surgical excision and follow up
  • May recur locally
  • No metastases or deaths
Gross description
  • Mean 8 cm (range, 2 - 17 cm), solid and circumscribed but not encapsulated
Microscopic (histologic) description
  • Unencapsulated circumscribed superficial fatty lesion with CD34+ spindle cells and abundant hemosiderin (Stanford University)
  • Spindle cells have vesicular nuclei and indistinct nucleoli with occasional hyperchromatism
  • Inflammatory background
  • No / minimal atypia
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #199:

Various images

Images hosted on other servers:

Various images

Positive stains
Negative stains
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