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Soft Tissue Tumors
Mixed type liposarcoma
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Reviewer: David Lucas, M.D., University of Michigan Health Systems (January 2009)
Revised: 14 June 2009, last major update June 2009
Definition
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● Mixture of myxoid/round cell, well differentiated/dedifferentiated and pleomorphic types
Epidemiology
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● Rare; affects elderly patients, usually in retroperitoneum
● Morphologic differences are due to differential expression of multiple genes (Pathology 2006;38:114)
Case reports
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● 45 year old woman with thigh tumor (Virchows Arch 2008;453:197)
● 50 year old man with retroperitoneal tumor (Am Surg 2008;74:1202
● Two cases (Jpn J Clin Oncol 2003;33:482)
Gross description
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● Large multinodular masses
● Cystic/solid; gray-white-yellow
Gross images
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Left-myxoid liposarcoma, Yellow-well differentiated liposarcoma,
right-well differentiated liposarcoma white-pleomorphic liposarcoma
Micro images
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Mixed well differentiated Mixed well differentiated
and myxoid liposarcoma and pleomorphic liposarcoma, S100+
End of Soft Tissue Tumors > Mixed type liposarcoma
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