Soft tissue
Adipose tissue
Nevus lipomatosus superficialis

Topic Completed: 1 August 2012

Revised: 20 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Nevus lipomatosus superficialis

Vijay Shankar, M.D.
Page views in 2018: 8,515
Page views in 2019 to date: 4,395
Cite this page: Shankar V. Nevus lipomatosus superficialis. website. Accessed June 26th, 2019.
Definition / general
  • Nodules of mature fat tissue within dermis
  • Either solitary or multiple
  • Also called nevus lipomatosus cutaneous superficialis and dermolipoma
  • Not a WHO diagnosis
  • First described in 1921 by Hoffman and Zurhelle
  • Considered to be a developmental anomaly or hamartoma
  • Uncommon
  • At birth or by age 20 years
Clinical features
  • Buttocks or upper thighs
  • Either solitary (more common) or multiple type of Hoffmann-Zurhelle (Tunis Med 2006;84:800)
Case reports
  • Excision - does not recur
Clinical images

Images hosted on other servers:

Lumbar region

Brown-red nodules

Gross description
  • Soft yellow papules
Microscopic (histologic) description
  • Mature adipocytes in dermis
  • No encapsulation or connection with subcutaneous fat
  • No distinct epidermal changes
Microscopic (histologic) images

Images hosted on other servers:

Dermal adipose tissue is continuous with underlying subcutis

Ectopic fat in mid to lower dermis

Various images

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