Soft tissue
Adipose tissue
Nevus lipomatosus superficialis

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 4 August 2016, last major update August 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Nevus lipomatosus superficialis

Definition / General
  • Nodules of mature fat tissue within dermis
  • Either solitary or multiple
Terminology
  • Also called nevus lipomatosus cutaneous superficialis and dermolipoma
  • Not a WHO diagnosis
  • First described in 1921 by Hoffman and Zurhelle
  • Considered to be a developmental anomaly or hamartoma
Epidemiology
  • Uncommon
  • At birth or by age 20 years
Clinical Features
  • Buttocks or upper thighs
  • Either solitary (more common) or multiple type of Hoffmann-Zurhelle (Tunis Med 2006;84:800)
Case Reports
Treatment
  • Excision - does not recur
Clinical Images

Images hosted on other servers:

Lumbar region

Brown-red nodules

Gross Description
  • Soft yellow papules
Micro Description
  • Mature adipocytes in dermis
  • No encapsulation or connection with subcutaneous fat
  • No distinct epidermal changes
Micro Images

Images hosted on other servers:

Dermal adipose tissue is continuous with underlying subcutis

Ectopic fat in mid to lower dermis



Various images