Soft Tissue Tumors - Nevus lipomatosus superficialis

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Soft Tissue Tumors

Adipose tissue

Nevus lipomatosus superficialis

Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 4 November 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Nodules of mature fat tissue within dermis
● Either solitary or multiple

Terminology
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● Also called nevus lipomatosus cutaneous superficialis and dermolipoma
● Not a WHO diagnosis
● First described in 1921 by Hoffman and Zurhelle
● Considered to be a developmental anomaly or hamartoma

Epidemiology
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● Uncommon
● At birth or by age 20 years

Clinical features
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● Buttocks or upper thighs
● Either solitary (more common) or multiple type of Hoffmann-Zurhelle (Tunis Med 2006;84:800)

Case reports
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● 7 year old girl with congenital lesion of calf (J Postgrad Med 2005;51:47)
● 12 year old girl with neck lesion (Indian J Dermatol Venereol Leprol 2006;72:66)
● 33 year old man with slow growing cutaneous plaque of lumbar region (Patholog Res Int 2011;2011:105973)
● 35 year old woman with thigh lesion (Archives of Iranian Medicine)
● 45 year old man with lower back lesion (Indian J Dermatol Venereol Leprol 1994;60:39)
● 51 year old man with lesion on pinna for 15 years (Dermatol Online J 2010;16:12)

Treatment and prognosis
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● Excision - does not recur

Clinical images
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Lumbar region

Pinna lesion

Brown-red nodules

Gross description
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● Soft yellow papules

Micro description
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● Mature adipocytes in dermis
● No encapsulation or connection with subcutaneous fat
● No distinct epidermal changes

Micro images
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Dermal adipose tissue is continuous with underlying subcutis

Ectopic fat in mid to lower dermis

Various images

Differential diagnosis
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● Fibroepithelial polyp
● Neurofibroma
● Nevus sebaceous

End of Soft Tissue Tumors > Adipose tissue > Nevus lipomatosus superficialis

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