Soft Tissue Tumors - Pelvic lipomatosis

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Soft Tissue Tumors

Adipose tissue

Pelvic lipomatosis

Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 4 November 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Lipomatosis in region of rectum or bladder, rarely in retroperitoneum (Stanford University)
● Also occurs in renal hilum, associated with chronic pyelonephritis, renal lithiasis and kidney atrophy
● Not a WHO diagnosis

Epidemiology
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● Rare
● Usually black men, median age 48 years, range 9-80 years
● Present with urological or digestive symptoms
● Associated with cystitis glandularis, cystitis cystica or cystitis follicularis in 75% of cases; may develop adenocarcinoma

Case reports
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● 32 year old hypertensive man with bilateral obstructive uropathy (Urol Int 2010;84:239)
● 51 year old man with painless hematuria (Incont Pelvic Floor Dysfunct 2008;2:124 (pdf))
● 58 year old man with bladder adenocarcinoma (Urol Oncol 2004;22:428)
● 70 year old man with gross hematuria and bilateral hydronephrosis (Nihon Hinyokika Gakkai Zasshi 2007;98:37)
● Two brothers with renal failure (Beijing Da Xue Xue Bao 2007;39:355)

Gross images
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Kidney shows increase in peripelvic adipose tissue, hydronephrosis and cortical atrophy

Micro description
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● Normal adipose tissue

Micro images
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Unremarkable adipose tissue

Associated cystitis glandularis

Differential diagnosis
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● Well differentiated liposarcoma: discrete mass, not in pelvis, atypical cells within fibromyxoid stroma

End of Soft Tissue Tumors > Adipose tissue > Pelvic lipomatosis

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