Soft tissue
Adipose tissue
Pleomorphic lipoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 4 August 2016, last major update August 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Pleomorphic lipoma [title]

See also: pleomorphic lipoma / spindle cell lipoma - general, spindle cell lipoma

Cite this page: Pleomorphic lipoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissueadiposepleomorphic.html. Accessed December 10th, 2016.
Definition / General
  • Mature adipocytes, dense collagen and floret giant cells in subcutaneous tissue of neck, back or shoulder
  • Usually dermal or beneath mucous membranes
Epidemiology
  • Rare - incidence is only 10% that of spindle cell lipoma
Treatment
  • Excision, only rarely recurs
Micro Description
  • Circumscribed tumor with adipocytes that are variable in size at low power
  • Prominent floret giant cells (hyperchromatic, multinucleated, wreath like nuclei) and small round hyperchromatic cells
  • May have spindle cells similar to spindle cell lipoma
  • No / rare lipoblasts, no prominent vascularity
Micro Images

Images hosted on PathOut servers:

Numerous pleomorphic and floret cells



Images hosted on other servers:

Various images

Cytology Description
Positive Stains
Negative Stains
Differential Diagnosis