Soft tissue
Skeletal muscle
Anaplastic rhabdomyosarcoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 26 September 2016, last major update November 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Anaplastic rhabdomyosarcoma

Terminology
  • In children (but not adults), includes cases previously called pleomorphic rhabdomyosarcoma
  • Not a WHO diagnosis
  • Most cases represent a variant of embryonal rhabdomyosarcoma
Case Reports
Prognosis and Treatment
  • Poor prognosis, particularly if anaplastic cells are aggregated in a clone-like cluster
Micro Description
  • Cells have enlarged, pleomorphic, hyperchromatic nuclei
  • Atypical polar mitotic figures
Additional References