Soft tissue
Skeletal muscle
Anaplastic rhabdomyosarcoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 26 September 2016, last major update November 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Anaplastic rhabdomyosarcoma

Cite this page: Anaplastic rhabdomyosarcoma. website. Accessed September 22nd, 2017.
  • In children (but not adults), includes cases previously called pleomorphic rhabdomyosarcoma
  • Not a WHO diagnosis
  • Most cases represent a variant of embryonal rhabdomyosarcoma
Case reports
Prognosis and treatment
  • Poor prognosis, particularly if anaplastic cells are aggregated in a clone-like cluster
Microscopic (histologic) description
  • Cells have enlarged, pleomorphic, hyperchromatic nuclei
  • Atypical polar mitotic figures
Additional references