Soft tissue
Approach to diagnosis

Author: Komal Arora, M.D. (see Authors page)

Revised: 25 July 2016, last major update July 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Diagnosis [title] soft tissue

Table of Contents
Definition / general
Cite this page: Approach to diagnosis. website. Accessed January 18th, 2018.
Definition / general
  • Modified from Sternberg:
    • 1) Is lesion reactive or neoplastic?
    • 2) Is lesion malignant? (necrosis favors malignancy)
    • 3) Is malignant lesion a sarcoma? (may be melanoma, carcinoma, lymphoma)
    • 4) What type of differentiation is present? - assign to phenotypic category or classify as round cell, spindle cell, epithelioid, other
    • 5) If sarcoma, what is the grade?