Soft tissue
Approach to diagnosis

Topic Completed: 1 July 2012

Minor changes: 11 September 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Diagnosis [title] soft tissue

Komal Arora, M.D.
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Table of Contents
Definition / general
Cite this page: Arora K. Approach to diagnosis. website. Accessed September 26th, 2020.
Definition / general
  • Modified from Sternberg:
    1. Is lesion reactive or neoplastic?
    2. Is lesion malignant? (necrosis favors malignancy)
    3. Is malignant lesion a sarcoma? (may be melanoma, carcinoma, lymphoma)
    4. What type of differentiation is present? - assign to phenotypic category or classify as round cell, spindle cell, epithelioid, other
    5. If sarcoma, what is the grade?
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