Soft tissue
Smooth muscle
Bizarre leiomyoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 29 September 2016, last major update November 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Bizarre leiomyoma

Cite this page: Bizarre leiomyoma. website. Accessed December 16th, 2017.
  • Also called symplastic, atypical, apoplectic leiomyoma
Clinical features
Case reports
Clinical images

Images hosted on other servers:

Scrotal mass

Thigh nodule

Microscopic (histologic) description
  • Large, atypical nuclei in otherwise normal appearing leiomyoma
  • No/rare mitotic figures
  • Suggested classification for vulvar tumors is based on number of features below (0 - 1: leiomyoma, 2: atypical leiomyoma, 3 - 4: leiomyosarcoma)
    • 5+ cm in greatest dimension
    • Infiltrative margins
    • 5+ mitotic figures per 10 HPF
    • Moderate to severe cytologic atypia (Am J Surg Pathol 1996;20:779)
Microscopic (histologic) images

Images hosted on other servers:

Smooth muscle cells with focal atypia

68 year old woman with thigh nodule (figures 2 - 5)

72 year old woman with nasal obstruction, rhinorrea, and epistaxis

Negative stains