Soft Tissue
Other tumors
Cutaneous

Author: Vijay Shankar, M.D.

Revised: 31 January 2018, last major update December 2014

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Soft Tissue Cutaneous[title]

Related topics: Epithelioid sarcoma, Proximal type

Page views in 2018: 163
Page views in 2019 to date: 117
Cite this page: Shankar, V. Cutaneous. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuecutaneous.html. Accessed June 25th, 2019.
Definition / general
  • Confined to skin or subcutaneous fat, with little/no involvement of deep soft tissues
  • 20% have history of prior trauma
  • Accurate diagnosis usually established only after repeated biopsies
Clinical images
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Foot

Gross description
  • Ulcerated papule or nodule on distal extremity of young adult
Microscopic (histologic) description
  • Pseudogranulomatous pattern, bland cytology
  • Monomorphous cell population
  • Hyalinized focally calcified stroma
  • Mummified remnants of necrotic epithelioid cells present
Microscopic (histologic) images
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4A-vimentin, 4B-EMA

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Forearm

Positive stains
Differential diagnosis
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