Soft tissue
Extraskeletal bone tumors
Aneurysmal bone cyst

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 10 August 2016, last major update November 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Aneurysmal bone cyst [title]

Cite this page: Aneurysmal bone cyst. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissueeskabc.html. Accessed December 8th, 2016.
Definition / General
  • Features identical to intraosseous aneurysmal bone cyst
  • Rapidly growing, benign mass of deep soft tissue of upper extremities, thigh or groin, without involvement of adjacent bones
  • Mean age 28 years, range 8 - 37 years
  • May recur locally if incompletely excised
Case Reports
Gross Description
  • Median 4 cm, range 2.5 - 9 cm, surrounded by thin rim of bone (Am J Surg Pathol 2002;26:64)
  • Hemorrhagic cystic spaces with fibrous septa
Gross Images

Images hosted on other servers:

Shoulder

Micro Description
  • Cystic spaces filled with blood
  • Fibrous septa composed of fibroblasts, osteoclast-type giant cells, woven bone
Micro Images

Images hosted on other servers:

Shoulder

Molecular / Cytogenetics Description
  • 46,XY, t(17;17)(p13;q12), similar to intraosseous aneurysmal bone cyst
  • Also t(16;17)(q22;p13)
  • USP6 locus rearrangement on chromosome 17p13 (J Bone Joint Surg Am 2011;93:e45)
Differential Diagnosis