Soft tissue
Extraskeletal bone tumors
Extraskeletal chondrosarcoma




Topic Completed: 1 November 2012

Revised: 21 March 2019

Copyright: 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Extraskeletal chondrosarcoma [title]

See also: Mesenchymal chondrosarcoma, Myxoid chondrosarcoma

Page views in 2018: 3,724
Page views in 2019 to date: 1,305
Cite this page: Shankar V. Extraskeletal chondrosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissueeskchondrosarcoma.html. Accessed April 25th, 2019.
Definition / general
  • Less aggressive than similar bone tumor
  • Usually adult extremities; also children and trunk
  • Metastases to lung
  • Embryonal chondrosarcoma: Rare, primitive appearance
Gross images

Images hosted on PathOut servers:

Hyaline, courtesy of Mark R. Wick, M.D.



Images hosted on other servers:

Thigh tumor

Fallopian tube tumor

Microscopic (histologic) description
  • Usually myxoid
  • Cords of small cells with acidophilic cytoplasm, occasional vacuoles, usually in myxoid stroma
  • Usually no obvious chondrocytes
Microscopic (histologic) images

Images hosted on PathOut servers:

Clear cell, courtesy of Mark R. Wick, M.D.



Images hosted on other servers:

Fallopian tube tumor

Positive stains
Negative stains
Electron microscopy description
  • Well developed endoplasmic reticulum, cytoplasmic filaments, glycogen
Molecular / cytogenetics description
  • t(9;22)(q22-31;q11-12): CHN-EWS fusion gene, is consistent marker for extraskeletal myxoid chondrosarcoma (Mod Pathol 1995;8:765)
Back to top