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General
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Epidemiology
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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Immature muscle cells and mesenchymal cells are often in central portion of tumor, with better differentiated skeletal muscle cells and mesenchymal cells at periphery

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Undifferentiated round mesenchymal cells and immature skeletal muscle cells within myxoid or edematous stroma

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Various images

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Pleomorphic, polygonal muscle cells


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Figure 1

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Figure 2


Fig 1: The bipolar, immature skeletal muscle cells have tapered eosinophilic cytoplasmic processes and closely resemble the myotubular stage of striated muscle development, and the undifferentiated cells have minimal cytoplasm and round or oval nuclei
Fig 2: Mucosal tumors have a pseudocambium layer of plasma cells and lymphocytes resembling embryonal rhabdomyosarcoma, but there is no atypia and no mitotic figures

Cellular fetal type rhabdomyoma:

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Tumor cells are arranged in fascicles with less stroma

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Immature skeletal muscle cells

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Ganglion cell-like rhabdomyoblasts

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Strap cells with abundant eosinophilic cytoplasm and cross striations

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Myxoid tumor of tongue (various images)

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PTAH shows cross striations

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Ganglion cell like rhabdomyoblasts or strap cells are arranged in patternless pattern with undifferentiated mesenchymal cells



Courtesy of Dr. Mark R. Wick:

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Base of tongue, juvenile

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Cellular variant

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Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Differential diagnosis
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End of Soft Tissue > Skeletal muscle > Fetal type rhabdomyoma



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