Soft tissue
Fibrohistiocytic tumors

Topic Completed: 3 October 2019

Minor changes: 6 October 2019

Copyright: 2019,, Inc.

PubMed Search: Soft tissue fibrohistiocytic[TI]

Brendan C. Dickson, M.D., M.Sc.
Page views in 2019: 174
Page views in 2020 to date: 310
Table of Contents
Definition / general
Cite this page: Dickson B. Fibrohistiocytic tumors - general. website. Accessed June 7th, 2020.
Definition / general
  • Due to controversy over the precise lineage of these tumors, these tumors are termed "so called" fibrohistiocytic tumors (Fletcher, WHO Classification of Tumours of Soft Tissue and Bone, 2013)
  • Tumors previously called MFH (malignant fibrous histiocytoma) are now called undifferentiated or unclassified sarcoma; they are subclassified based on cell morphology: undifferentiated pleomorphic sarcoma, spindle cell, epithelioid cell and round cell
  • It remains to be seen how this will be modified in the upcoming WHO Classification
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