Soft tissue
Fibroblastic / myofibroblastic tumors
Gardner type fibroma

Author: Komal Arora, M.D. (see Authors page)

Revised: 19 August 2016, last major update July 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Gardner type fibroma

Cite this page: Gardner type fibroma. website. Accessed October 24th, 2016.
Definition / General
  • Benign soft tissue lesion with thick, haphazard collagen and bland fibroblasts that entrap adjacent tissue
  • 90% associated with FAP / Gardner’s syndrome / APC germline mutation
  • Uncommon
  • Affects infants, children and teenagers
  • May be initial diagnostic clue to Gardner’s syndrome and APC mutations (Am J Surg Pathol 2001;25:645)
  • 45% develop desmoid-type fibromatosis
  • Similar histology to nuchal-type fibroma (Pathol Int 2004;54:523, Am J Surg Pathol 2000;24:1563)
  • Superficial or deep soft tissue
  • Various sites
Case Reports
Gross Description
  • 1 - 10 cm, poorly circumscribed, firm, rubbery, plaque-like, white to tan-pink cut surface with trapped fat in yellow areas
Micro Description
  • Thick, haphazardly arranged collagen bundles, hypocellular bland fibroblasts, small blood vessels, plaque-like growth pattern with infiltration of adjacent structures
Positive Stains