Soft tissue
Fibroblastic / myofibroblastic tumors
Giant cell angiofibroma

Author: Komal Arora, M.D. (see Authors page)

Revised: 19 August 2016, last major update July 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Giant cell angiofibroma

Cite this page: Giant cell angiofibroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuegiantcellangiofibroma.html. Accessed December 4th, 2016.
Definition / General
Sites
Epidemiology
  • Median age 45 years
  • More common in men in eyelid / orbital sites, more common in women elsewhere
  • Often slow growing painful mass
Case Reports
Treatment
  • Excision, does not recur
Gross Description
  • Well-circumscribed with variable capsule, median 3 cm (larger in extra-orbital regions), may have hemorrhagic or cystic cut surface
Gross Images

Images hosted on PathOut servers:

Courtesy of Mark R. Wick, M.D.

Micro Description
  • Cellular areas with bland round to spindle cells in myxocollagenous stroma with small-medium thick walled vessels and multinucleated giant stromal cells that line ectatic vascular spaces
Micro Images

Images hosted on PathOut servers:

Courtesy of Mark R. Wick, M.D.



Images hosted on other servers:

Various images

Positive Stains
Molecular / Cytogenetics Description