Soft tissue
Intermediate (locally aggressive / rarely metastasizing)
Kaposiform hemangioendothelioma

Topic Completed: 1 November 2012

Minor changes: 15 September 2020

Copyright: 2002-2020,, Inc.

PubMed search: Kaposiform [title] hemangioendothelioma

Vijay Shankar, M.D.
Page views in 2019: 1,980
Page views in 2020 to date: 2,606
Cite this page: Shankar V. Kaposiform hemangioendothelioma. website. Accessed November 30th, 2020.
Definition / general
  • Rare, locally aggressive; tumor of infants and children; affects skin (75%), retroperitoneum (18%), bone
  • Death due to extensive disease and severe coagulopathy (Kasabach-Merritt syndrome), although no metastatic potential (Mod Pathol 2001;14:1087)
  • Usually initial tumor is cutaneous
Case reports
Clinical images

Contributed by Dr. Mark R. Wick

Images hosted on other servers:

Tonsillar mass

Microscopic (histologic) description
  • Infiltrating nodules and sheets of compact spindle cells with slit-like lumina
Microscopic (histologic) images

Contributed by Dr. Mark R. Wick

Case #401

Low power view


CD31 (20x)




Images hosted on other servers:

Glomeruloid nests of spindled and epithelioid cells

Tonsillar mass

Differential diagnosis
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