Soft tissue
Vascular: intermediate (locally aggressive / rarely metastasizing)
Kaposiform hemangioendothelioma


Topic Completed: 1 November 2012

Revised: 9 September 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed search: Kaposiform [title] hemangioendothelioma

Vijay Shankar, M.D.
Page views in 2018: 1,377
Page views in 2019 to date: 1,223
Cite this page: Shankar V. Kaposiform hemangioendothelioma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuehemangioendotheliomakaposiform.html. Accessed September 20th, 2019.
Definition / general
  • Rare, locally aggressive; tumor of infants and children; affects skin (75%), retroperitoneum (18%), bone
  • Death due to extensive disease and severe coagulopathy (Kasabach-Merritt syndrome), although no metastatic potential (Mod Pathol 2001;14:1087)
  • Usually initial tumor is cutaneous
Case reports
Clinical images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick



Images hosted on other servers:

Tonsillar mass

Microscopic (histologic) description
  • Infiltrating nodules and sheets of compact spindle cells with slit-like lumina
Microscopic (histologic) images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick



Case of the Week #401:

Low power view

20x

CD31 (20x)

CD34

SMA

Vimentin



Images hosted on other servers:

Glomeruloid nests of spindled and epithelioid cells

"Cannon ball" appearance

Slit-like lumens

VEGFR3+


Tonsillar mass

Differential diagnosis
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