Soft tissue
Fibroblastic / myofibroblastic tumors
Intravascular fasciitis

Author: Lauren N. Stuart M.D., M.B.A.
Editor: Jerad M. Gardner, M.D.

Revised: 30 January 2018, last major update April 2014

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Intravascular fasciitis soft tissue pathology

See also: Nodular fasciitis, Proliferative funiculitis, Cranial fasciitis

Page views in 2018: 273
Page views in 2019 to date: 278
Cite this page: Stuart, L.N. Intravascular fasciitis. website. Accessed August 21st, 2019.
Definition / general
  • Variant of nodular fasciitis that involves wall and lumen of small to medium-sized veins and arteries (Am J Surg Pathol 1981;5:29)
  • Slower growth than classic nodular fasciitis but same behavior
  • Uncommon
  • Typically seen in 1st through 3rd decades, but can occur at any age
  • Slightly more common in men (Head Neck Pathol 2012;6:140)
  • Most often found in upper extremity or head and neck region
  • Less common sites include the lower extremity and trunk
  • Unclear
Case reports
Gross description
  • Usually 2 cm or less
  • Nodular or plexiform
Microscopic (histologic) description
  • Resembles nodular fasciitis (proliferation of plump spindle cells in a loose "tissue culture" arrangement), but with a less prominent mucoid matrix and numerous osteoclast-like giant cells (J Cutan Pathol 2011;38:63)
  • May be intra- or extravascular
Microscopic (histologic) images

Images hosted on PathOut servers:
AFIP images:

Large focus of nodular fasciitis
protrudes into vascular space

Cellular proliferation
has edematous background
characteristic of nodular fasciitis

Images hosted on PathOut servers:

Low power

High power

Intravascular proliferation

Initial biopsy


Positive stains
Differential diagnosis
Back to top