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Soft tissue
Fibroblastic / myofibroblastic tumors
Intranodal palisaded myofibroblastoma

Reviewer: Lauren N. Stuart M.D., M.B.A. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.
Revised: 15 April 2013, last major update April 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

Definition
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Terminology
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Epidemiology
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Sites
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Pathophysiology
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Clinical features
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Prognostic factors
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Case reports
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Treatment
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Gross description
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Gross images
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Lymph node with areas of hemorrhage

Micro description
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5 key features:
  1. Spindle cell proliferation surrounded by hemorrhage and collagenous pseudocapsule; growing nodule compresses remaining nodal tissue
  2. Bland spindle cells with areas of nuclear palisading
  3. Intraparenchymal hemorrhage and red blood cell extravasation
  4. So-called amianthoid fibers
  5. Extra- and intracellular fuchsinophilic bodies (best seen with SMA stain, Arch Pathol Lab Med 2007;131:306)
Micro images
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Figure 1
Various images
Various images
Fig 1: Amianthoid fibers composed of a central vessel surrounded by a core of collagen with peripheral spokes, strongly stained by Van Gieson (elastin)

Various images
Various images

Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Differential diagnosis
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End of Soft tissue > Fibroblastic / myofibroblastic tumors > Intranodal palisaded myofibroblastoma


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