Soft tissue tumors
Benign vascular tumors
Microvenular hemangioma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 21 September 2016, last major update November 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: microvenular hemangioma

Cite this page: Microvenular hemangioma. website. Accessed October 28th, 2016.
Definition / General
  • Dermal proliferation of small, irregular branching capillaries and venules with inconspicuous lumina
  • Rare; < 50 cases reported
  • Young to middle aged adults
  • Often trunk or limbs
  • May be form of acquired venous hemangioma
  • Microcapillary hemangioma: similar histology, but occurs in young women taking oral contraceptives or during pregnancy
Clinical Features
Case Reports
  • Excision is curative
Gross Images
Images hosted on other servers:

Well defined, oval red lesion

Micro Description
  • Dermal proliferation of small, irregular branching capillaries and venules with inconspicuous lumina
  • Endothelial cells may be plump, but no atypia
  • Stroma is collagenous
  • Variable lymphocytes
  • No fat invasion, although may grow along collagenous septa of subcutis
  • No spindle cells
Micro Images
Images hosted on PathOut server:

Case of the Week #80:

Images hosted on other servers:

Dermal vascular proliferation

HHV8+ tumor

Positive Stains
Differential Diagnosis
  • Acquired (tufted) angioma: multiple vascular lobules similar to pyogenic granuloma but more cellular, resembling cannonballs
  • Kaposi's sarcoma - patch stage: irregular vascular spaces are anastomosing but not collapsed, and are accompanied by atypical endothelial cells, eosinophilic hyaline globules, plasma cells and fascicles of spindle cells; may be irregular dissection of collagen bundles by vessels; spindle cells are HHV8+, patients are HIV+ (Am J Clin Pathol 2004;121:335)
  • Kaposiform hemangioendothelioma: also has slit-like lumina, but they are due to nodules and sheets of compact spindle cells; affects the skin or retroperitoneum of infants and children, may be associated with severe coagulopathy
  • Sclerosing hemangioma
  • Statis related change