Soft tissue
Peripheral nerve
Epithelioid MPNST

Author: Vijay Shankar, M.D.

Revised: 30 January 2018, last major update November 2012

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Epithelioid MPNST

See also: malignant peripheral nerve sheath tumor (MPNST), malignant triton

Page views in 2018: 1,133
Page views in 2019 to date: 604
Cite this page: Shankar, V. Epithelioid MPNST. website. Accessed June 20th, 2019.
Definition / general
  • 5% of MPNST
  • Plump epithelioid cells with acidophilic cytoplasm
  • Most neurofibromas with malignant transformation are epithelioid, but most epithelioid MPNST are NOT associated with NF1
Case reports
Clinical images

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Microscopic (histologic) images

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Epitheloid type, courtesy of Mark R. Wick, M.D.

S100, courtesy of Mark R. Wick, M.D.

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Site unspecified: Fig 2 & 3a


Positive stains
Negative stains
Differential diagnosis
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