Soft tissue
Benign vascular tumors
Myopericytoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 19 September 2016, last major update November 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: myopericytoma [title] soft tissue

Definition / General
  • Also called perivascular myoid tumor
  • Usually adults, 60% male, median age 52 years, youngest case was age 10
  • Affects skin (dermis or subcutis) or soft tissues of extremities, rarely head or trunk
Case Reports
Treatment
  • Excision; only rarely recurs
Clinical Images
Images hosted on other servers:

Lower leg

Dorsal nose

Gross Images
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Multiple facial masses

Micro Description
  • Thin walled vessels and concentric, perivascular arrangement of plump spindle to round myoxid cells
  • May have hemangiopericytoma-like areas
  • Occasional prominent atypia and mitotic activity
  • Rarely infiltrative
  • No giant cells (Am J Surg Pathol 2006;30:104)
  • Rarely has lipomatous component (Cir Esp 2012;90:331)
Micro Images
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Oval cells with eosinophilic cytoplasm

Well circumscribed spindle cell tumor

Lung tumor: 3A-SMA; 3B-vimentin, 3C-CD34

(a) Unencapsulated neoplasm in deep dermis extends
into subcutis (arrows); (b) bland round ovoid cells with
concentric perivascular pattern and many thin walled
branching staghorn vessels
Positive Stains
Differential Diagnosis