Soft tissue
Benign vascular tumors

Author: Vijay Shankar, M.D.

Revised: 12 September 2018, last major update November 2012

Copyright: (c) 2002-2018,, Inc.

PubMed search: Myopericytoma [title] soft tissue

Cite this page: Shankar, V. Myopericytoma. website. Accessed December 16th, 2018.
Definition / general
  • Also called perivascular myoid tumor
  • Usually adults, 60% male, median age 52 years, youngest case was age 10
  • Affects skin (dermis or subcutis) or soft tissues of extremities, rarely head or trunk
Case reports
  • Excision; only rarely recurs
Clinical images

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Lower leg

Dorsal nose

Gross images

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Multiple facial masses

Microscopic (histologic) description
  • Thin walled vessels and concentric, perivascular arrangement of plump spindle to round myoxid cells
  • May have hemangiopericytoma-like areas
  • Occasional prominent atypia and mitotic activity
  • Rarely infiltrative
  • No giant cells (Am J Surg Pathol 2006;30:104)
  • Rarely has lipomatous component (Cir Esp 2012;90:331)
Microscopic (histologic) images

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Oval cells with eosinophilic cytoplasm

Well circumscribed spindle cell tumor

Lung tumor (fig 3):
3B: vimentin
3C: CD34

(a) Unencapsulated neoplasm in deep dermis extends into subcutis (arrows); (b) bland round ovoid cells with concentric perivascular pattern and many thin walled branching staghorn vessels

Positive stains
Differential diagnosis