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General
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Terminology
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Epidemiology
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Sites
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Radiology
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Case reports
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Treatment
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Clinical images
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Various images

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Various images

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CT scan, courtesy of Dr. Mark R. Wick

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MRI, courtesy of Dr. Mark R. Wick

Gross description
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Gross images
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Bone fragment from abdominal wall

Micro description
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Micro images
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Courtesy of Dr. Mark R. Wick



AFIP Images:
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Mature bone at periphery, fibrous tissue resembling nodular fasciitis at center, osteoid in between

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Fibroblastic and myofibroblastic cells in center of lesion resemble nodular fasciitis, with nuclear uniformity

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Osteoid is broader than in osteosarcoma

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Fig 1: Osteoblasts have large nuclei with prominent nucleoli, but clues to benign nature of lesion are reactive fibrous areas Fig 2: Osteoid deposition is uniform, and nuclei are enlarged but not pleomorphic

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Osteoid undergoing mineralization



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2x

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10x

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40x

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Various images of thigh lesion

Cytology images
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Hip mass with FNA

Positive stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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End of Soft Tissue > Fibroblastic / myofibroblastic tumors > Myositis ossificans



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