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Soft tissue tumors
Peripheral nerve tumors
Myxopapillary ependymoma
Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 6 March 2013, last major update November 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
General
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- Usually spinal cord tumor, may arise is soft tissue in sacrococcygeal area separate from cord
- Resembles pilonidal cyst clinically, but 20% metastasize
Case reports
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Gross description
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- Well circumscribed, easily enucleated
Gross images
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Two ovoid mass
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Micro description
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- Resembles CNS tumor
- Small blue cells forming well defined perivascular structures, surrounded by dense fibrous tissue
Micro images
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Epithelioid cells with some cytoplasmic clearing
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Cribriform pattern
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Solid sheets and cords
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L: S100; R: GFAP
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L: AE1AE3; R: CAM5.2
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Columnar cells
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Radial processes
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Positive stains
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Differential diagnosis
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- Ependymal rests: clusters of cells < 0.5 cm in dermis/subcutaneous tissue near pilonidal sinuses
End of Soft tissue tumors > Peripheral nerve tumors > Myxopapillary ependymoma
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