Soft tissue
Infections, inflammation and hematomas
Necrotizing fasciitis

Author: Komal Arora, M.D. (see Authors page)

Revised: 27 July 2016, last major update July 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Necrotizing fasciitis [title] soft tissue

Definition / General
  • Uncommon fulminant soft tissue infection characterized by extensive fascial necrosis
  • Usually due to group A streptococci, also community-acquired MRSA (Surg Infect (Larchmt) 2008;9:469)
  • May be due to Clostridium perfringens and cause gas gangrene (Cases J 2008;1:252)
Clinical Features
Case Reports
Treatment
Clinical Images

Images hosted on other servers:

Gas gangrene

Right shoulder

Left leg

Micro Images

Images hosted on other servers:

Infected tissue with gas-inclusion between the muscle fibers

Gram positive rods

Gluteal gas gangrene with necrotizing fasciitis

Gas gangrene



Necrotic muscle with gas bubbles but minimal inflammation

Leg lesion

Necrotizing fasciitis and panniculitis (pneumococci)

Pneumococcal sepsis



Septic thrombus

Associated vasculitis

Gram stain