Soft tissue
Peripheral nerve
Nerve - normal

Author: Vijay Shankar, M.D.

Revised: 30 January 2018, last major update November 2012

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Nerve [title] soft tissue

Table of Contents
Definition / general
Cite this page: Shankar, V. Nerve - normal. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuenervenormal.html. Accessed October 20th, 2018.
Definition / general
  • Composed of axons, Schwann cells, perineurial cells and fibroblasts in epineurium (outer sheath)
  • Perineurium: surrounds each nerve fascicle, is continuous with pia mater of CNS
  • Perineurial cells: derived from fibroblasts; EMA+, S100-
  • Schwann cells: neuroectodermally derived cells that resemble fibroblasts, but strongly S100+, intimately related to axons (by EM), have continuous basal lamina that coats the cell facing the endoneurium