Soft tissue
Peripheral nerve
Nerve - normal

Topic Completed: 1 November 2012

Minor changes: 22 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Nerve [title] soft tissue

Vijay Shankar, M.D.
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Page views in 2020 to date: 372
Table of Contents
Definition / general
Cite this page: Shankar V. Nerve - normal. website. Accessed June 4th, 2020.
Definition / general
  • Composed of axons, Schwann cells, perineurial cells and fibroblasts in epineurium (outer sheath)
  • Perineurium: surrounds each nerve fascicle, is continuous with pia mater of CNS
  • Perineurial cells: derived from fibroblasts; EMA+, S100-
  • Schwann cells: neuroectodermally derived cells that resemble fibroblasts, but strongly S100+, intimately related to axons (by EM), have continuous basal lamina that coats the cell facing the endoneurium
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