Soft tissue tumors
Peripheral nerve tumors
Nerve - normal
Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 6 March 2013, last major update November 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
End of Soft tissue tumors > Peripheral nerve tumors > Nerve - normal
- Composed of axons, Schwann cells, perineurial cells and fibroblasts in epineurium (outer sheath)
- Perineurium: surrounds each nerve fascicle, is continuous with pia mater of CNS
- Perineurial cells: derived from fibroblasts; EMA+, S100-
- Schwann cells: neuroectodermally derived cells that resemble fibroblasts, but strongly S100+, intimately related to axons (by EM), have continuous basal lamina that coats the cell facing the endoneurium
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