Soft tissue
Peripheral nerve
Nerve sheath myxoma

Topic Completed: 1 November 2012

Revised: 26 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Nerve sheath myxoma [title]

Vijay Shankar, M.D.
Page views in 2018: 4,969
Page views in 2019 to date: 4,671
Cite this page: Shankar V. Nerve sheath myxoma. website. Accessed October 15th, 2019.
Definition / general
  • Controversial tumor due to disputed relationship with neurothekeoma
  • Skin, soft tissue, intraspinal
  • Resembles myxoma but plumper, epithelial-like cells; fascicular or plexiform arrangement
  • Based on the amount of myxoid stroma, nerve sheath myxoma is divided into myxoid (classical), mixed and cellular types
Case reports
Clinical images

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Tender, solitary firm papule

Microscopic (histologic) description

Images hosted on PathOut servers:

Cutaneous, courtesy of Mark R. Wick, M.D.

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Lower leg lesion

Gingival lesion is well demarcated

Thick, short collagen bundles and focal myxoid areas



Positive stains
Differential diagnosis
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