• Controversial tumor due to disputed relationship with neurothekeoma
• Skin, soft tissue, intraspinal
• Resembles myxoma but plumper, epithelial-like cells; fascicular or plexiform arrangement
• Based on the amount of myxoid stroma, nerve sheath myxoma is divided into myxoid (classical), mixed and cellular types

• 32 year old woman with painless enlarging gingival mass (Head Neck Pathol 2010;4:242)
• 33 year old woman with painful leg lesion (Dermatol Online J 2007;13:14)

Tender, solitary firm papule

Lower leg lesion

Gingival lesion is well demarcated

Thick, short collagen bundles and focal myxoid areas

S100

NSE

• S100 (sporadic)
  

• Myxoid neurofibroma: S100+ (strong)
• Perineurioma

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).