Soft tissue
Peripheral nerve

Topic Completed: 1 September 2016

Revised: 26 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Neuroma [title] soft tissue

See also: amputation / traumatic, granular cell traumatic, morton, palisaded encapsulated

Vijay Shankar, M.D.
Page views in 2018: 9,439
Page views in 2019 to date: 7,271
Cite this page: Shankar V. Neuroma. website. Accessed September 22nd, 2019.
Definition / general
  • Benign nonneoplastic overgrowth of nerve fibers and Schwann cells
  • Usually post-traumatic; proximal nerve regenerates into a tangled mass of nerve fibers if it does not meet the distal end
  • Painful
Case reports
Microscopic (histologic) description
  • Axons, Schwann cells, perineurial fibroblasts, also scar
Microscopic (histologic) images

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Positive stains
  • CD68 (Schwann cells-become phagocytic)
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