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See subtypes below: Cranial fasciitisIntravascular fasciitisProliferative funiculitis

General
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Epidemiology
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Case reports
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Treatment
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Clinical images
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Mammogram, c/o Dr. Mark R. Wick

Gross description
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Gross images
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Hyperpigmented nodule

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Courtesy of Dr. Mark R. Wick

Micro description
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Micro images
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Images from AFIP:

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Fig 1: Subcutaneous tumor is partially circumscribed nodule infiltrating focally along fascial planes
Fig 2: Focal infiltration into fat, with evenly distributed granulation tissue-like vessels throughout the lesion
Fig 3: Gently curving C and S shaped fascicles of myofibroblastic cells exhibit a characteristic "torn Kleenex" pattern
Fig 4: Focal storiform pattern is suggestive of fibrous histiocytoma
Fig 5: Plump spindled myofibroblastic cells and extravasated red blood cells

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Figure 8

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Cystic degeneration


Fig 6: Mitotic figures but no abnormal forms
Fig 7: Focally more collagenous stroma with skeletal muscle involvement
Fig 8: Osteoclastic giant cells are present in less collagenous areas, suggesting a variant of MFH

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Figure 9

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Figure 10

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Figure 11


Fig 9: Hyalinized variant resembles keloid or fibromatosis
Fig 10: Vague zonation pattern with bone formation in lower right
Fig 11: Island of new bone surrounded by myofibroblastic cells

Courtesy of Dr. Mark R. Wick:

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Organizing



Case of the Week #65 / tumor of wrist:

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Other images::

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Leg lesion

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Resembles fibroblast culture

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Myofibroblasts and staghorn blood vessels

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"Tram track" pattern

Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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Cranial fasciitis
Reviewer: Ricardo M. Mendoza, M.D. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.

General
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Epidemiology
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Sites
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Pathophysiology
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Etiology
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Clinical features
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Radiology
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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Resembles usual nodular fasciitis

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Spindle cells lack cytologic atypia

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Increased mitotic activity

Positive stains
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Negative stains
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Differential diagnosis
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Intravascular fasciitis
Reviewer: Lauren N. Stuart, M.D., M.B.A. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.

General
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Epidemiology
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Sites
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Etiology
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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AFIP:
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Fig. 1: Large focus of nodular fasciitis protrudes into vascular space
Fig. 2: Cellular proliferation has edematous background characteristic of nodular fasciitis

Other images:
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Low power

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High power

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Intravascular proliferation

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Initial biopsy

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Re-excision

Positive stains
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Negative stains
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Differential diagnosis
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Proliferative funiculitis
Reviewer: Lauren N. Stuart, M.D., M.B.A. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.

General
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Terminology
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Epidemiology
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Sites
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Etiology
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Clinical features
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Laboratory
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Radiology
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Prognostic factors
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Treatment
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Gross description
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Gross / clinical images
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Inguinal tumor

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Tumor in undescended testis

Micro description
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Clinical images
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Spindle cell proliferation

Positive stains
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Negative stains
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Differential diagnosis
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End of Soft Tissue > Fibroblastic / myofibroblastic tumors > Nodular fasciitis



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