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Soft tissue tumors
Perivascular epithelioid cell family of tumors (PEComas) of soft tissue
General

Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 12 November 2014, last major update November 2012
Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.

See subtype below: sclerosing PEComa

Definition
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Epidemiology
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Prognostic factors
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Case reports
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Treatment
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Gross images
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Uterus: polypoid gray-white mass
Uterus: polypoid mass
Micro description
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Micro images
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Bladder:
Epithelioid cells with abundant eosinophilic cytoplasm
MelanA+
Smooth muscle actin+

Cervix:
Mass with central circular core
Infiltrative border
Spindled to epithelioid areas
Degenerative atypia
Pecomatosis
Ovarian hila
HMB45+

Head and neck:
Nasal PEComa
Larynx

Kidney:       Prostate:     Site unknown:
Figure 2b: MelanA+ tumor
Epithelioid cells are HMB45+
Spindle cells

Soft tissue (Case of the Week #283):
Alpha smooth muscle actin
HMB45 - low power
HMB45 - high power

Uterus:
Tumor, lung metastases, HMB45+
Malignant epithelioid cells
Actin+ (red) and HMB45+ (brown)
HMB45+ recurrent tumor

Unspecified:
Malignant tumor

Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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Sclerosing PEComa
Definition
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Case reports
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Treatment
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Gross description
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Gross images
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Well-circumscribed, encapsulated tumor
Micro description
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Micro images
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Nests of clear cells in sclerotic stroma
Various stains
Positive stains
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Negative stains
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End of Soft tissue tumors > Perivascular epithelioid cell family of tumors (PEComas) of soft tissue > General


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