Soft tissue
Peripheral nerve
Reticular variant

Author: Vijay Shankar, M.D.

Revised: 30 January 2018, last major update November 2012

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Perineurioma reticular variant

See also: perineurioma, sclerosing

Page views in 2018: 144
Page views in 2019 to date: 115
Cite this page: Shankar, V. Reticular variant. website. Accessed September 24th, 2019.
Definition / general
  • Median age 43, range 34 - 61, 2/3 women in small study
  • Upper extremity, gingiva, inguinal region
  • Appears to have benign behavior
Case reports
Gross description
  • Median 4 cm, range 1.5 to 10 cm
Microscopic (histologic) description
  • Lace-like or reticular ("net-like") growth pattern of anastomosing cords of fusiform cells with bipolar cytoplasmic processes and pale eosinophilic cytoplasm
  • Central nuclei
  • Commonly ransitions to more cellular areas (Am J Surg Pathol 2001;25:485)
  • Collagenous to myxoid stroma
  • Cystic areas common
  • No mitotic figures
  • Mild / moderate nuclear atypia (may be degenerative)
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Negative stains
Differential diagnosis
Back to top