Soft tissue
Uncertain differentiation
Pleomorphic hyalinizing angiectatic tumor

Topic Completed: 1 August 2012

Minor changes: 10 September 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Pleomorphic hyalinizing angiectatic tumor [title]

Vijay Shankar, M.D.
Page views in 2019: 3,215
Page views in 2020 to date: 2,800
Cite this page: Shankar V. Pleomorphic hyalinizing angiectatic tumor. website. Accessed November 27th, 2020.
Definition / general
  • Low grade malignancy of adults (median age 51 years), often in extremities or trunk
  • May be derived from stromal fibroblasts or primitive undifferentiated mesenchyme
Case reports
  • Wide local excision, but 20% recur, rarely as sarcoma
Microscopic (histologic) description
Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.

Various images

Cytology description
Positive stains
Negative stains
Molecular / cytogenetics description
  • Case report of 2 unbalanced translocations involving chromosomes 1 and 3 and chromosomes 1 and 10, with a karyotype of 45,XX,der(1)t(1;3)(p31;q12),-3,der(10)t(1;10)(p31;q25)[11]/46,XX4 (Hum Pathol 2012;43:121)
Differential diagnosis
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