Soft tissue
Fibrohistiocytic tumors
Pleomorphic hyalinizing angiectatic tumor

Author: Vijay Shankar, M.D.

Revised: 30 January 2018, last major update August 2012

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Pleomorphic hyalinizing angiectatic tumor [title]

Cite this page: Shankar, V. Pleomorphic hyalinizing angiectatic tumor. website. Accessed November 14th, 2018.
Definition / general
  • Low grade malignancy of adults (median age 51 years), often in extremities or trunk
  • May be derived from stromal fibroblasts or primitive undifferentiated mesenchyme
Case reports
  • Wide local excision, but 20% recur, rarely as sarcoma
Microscopic (histologic) description
Microscopic (histologic) images

Images hosted on PathOut servers:

Courtesy of Mark R. Wick, M.D.

Images hosted on other servers:

Various images

Cytology description
Positive stains
Negative stains
Molecular / cytogenetics description
  • Case report of 2 unbalanced translocations involving chromosomes 1 and 3 and chromosomes 1 and 10, with a karyotype of 45,XX,der(1)t(1;3)(p31;q12),-3,der(10)t(1;10)(p31;q25)[11]/46,XX4 (Hum Pathol 2012;43:121)
Differential diagnosis