Fibroblastic / myofibroblastic tumors
Reviewer: Cliff Sullivan, M.D. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.
Revised: 9 June 2013, last major update June 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Reactive, angiomyxoid tumor-like mass near joints and ligaments
- Not a WHO diagnosis
- Poorly documented in literature
- Generally a complication of prior joint disease (e.g. degenerative joint disease, ruptured ganglion cyst), dislocation, or trauma
- Low power: separate vascular and nonvascular regions; vascular region has cluster of thick vessels, often in nodular pattern, with pericyte cuff in myxoid substance
- High power: evenly disbursed spindle cells with bipolar and stellate cells and scattered lymphocytes and histiocytes; histiocytes may contain vacuoles and resemble lipoblasts; may have cysts, some resembling ganglion cysts, with or without a synovial lining; occasionally have dense scar
Angiomyxoid lesion with vessels thicker than capillaries
- Myxoid liposarcoma: uniform round cells, delicate branching "chicken wire" vasculature, scattered uni- or bi-vacuolated monotonous lipoblasts
- Myxoma: hypocellular, stellate cells only; no prominent vasculature
End of Soft tissue > Fibroblastic / myofibroblastic tumors > Proliferative peribursitis
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