Soft tissue
Peripheral nerve tumors
Ancient schwannoma


Topic Completed: 1 November 2012

Minor changes: 24 October 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Ancient schwannoma [title]

Vijay Shankar, M.D.
Page views in 2019: 4,909
Page views in 2020 to date: 2,262
Cite this page: Shankar V. Ancient schwannoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissueschwannomaancient.html. Accessed July 10th, 2020.
Definition / general
  • Degenerative change to tumors, usually large and of long duration, deep within retroperitoneum
  • Cyst formation, calcification, hemorrhage (stromal hemosiderin), hyalinization, histiocytic infiltration, severe nuclear atypia (nuclear hyperchromasia, irregular nuclear shapes)
  • No mitotic figures
Case reports
Gross images

Images hosted on PathOut servers:

Well circumscribed tumor

Cut section with variegated appearance,
cystic areas, hemorrhage and calcification

Microscopic (histologic) images

Images hosted on PathOut servers:

Ancient change, courtesy of Mark R. Wick, M.D.



Case of the Week #334:

Encapsulated mass with calcification

Hypercellular and hypocellular areas

Myxoid change

Hyalinized blood vessels

Enlogated cells with cigar shaped nuclei



Hypercellular areas with palisading

Hyalinized blood vessels

Cystic areas

Cystic areas and blood vessels



Areas of ossification

S100



Images hosted on other servers:

Various images

Hypopharyngeal tumor



Thigh mass mimicking malignancy

Abdominal wall mass

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