Soft tissue
Peripheral nerve
Other benign
Schwannoma-microcystic / reticular


Topic Completed: 1 November 2012

Minor changes: 9 September 2020

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PubMed Search: Microcystic-reticular variant

Vijay Shankar, M.D.
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Cite this page: Shankar V. Schwannoma-microcystic / reticular. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissueschwannomamicrocystic.html. Accessed November 30th, 2020.
Definition / general
Case reports
Gross description
  • Median 4 cm, range 0.4 to 23 cm
Microscopic (histologic) description
  • Circumscribed, unencapsulated tissue (encapsulated if in subcutis)
  • Infiltrative in visceral locations
  • Microcystic and reticular growth pattern with anastomosing and intersecting spindle cells, distributed around islands of myxoid or collagenous / hyalinized stroma
  • Round / oval nuclei with tapering, indistinct nucleoli
  • 0 - 3 MF / 50 HPF
  • No necrosis, no pleomorphism
Microscopic (histologic) images

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GI tract

Positive stains
Negative stains
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