Soft tissue
Peripheral nerve tumors
Schwannoma, microcystic-reticular variant

Topic Completed: 1 November 2012

Revised: 1 November 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Microcystic-reticular variant

Vijay Shankar, M.D.
Page views in 2019: 537
Page views in 2020 to date: 102
Cite this page: Shankar V. Schwannoma, microcystic-reticular variant. website. Accessed February 21st, 2020.
Definition / general
Case reports
Gross description
  • Median 4 cm, range 0.4 to 23 cm
Microscopic (histologic) description
  • Circumscribed, unencapsulated tissue (encapsulated if in subcutis)
  • Infiltrative in visceral locations
  • Microcystic and reticular growth pattern with anastomosing and intersecting spindle cells, distributed around islands of myxoid or collagenous / hyalinized stroma
  • Round / oval nuclei with tapering, indistinct nucleoli
  • 0 - 3 MF / 50 HPF
  • No necrosis, no pleomorphism
Microscopic (histologic) images

Images hosted on other servers

GI tract


Positive stains
Negative stains
Electron microscopy images

Images hosted on other servers

Irregular cell borders, elongated nuclei

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