Soft tissue
Smooth muscle
Smooth muscle tumors-general

Topic Completed: 1 November 2012

Minor changes: 17 September 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Smooth muscle tumors [title]

Vijay Shankar, M.D.
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Cite this page: Shankar V. Smooth muscle tumors-general. website. Accessed October 24th, 2020.
Microscopic (histologic) description
  • Tumor cells resemble smooth muscle with easily visible, often fibrillar and eosinophilic cytoplasm, usually in long bundles or fascicles
  • Nucleus is long, oval and round at both ends, often with cytoplasmic vacuole at one end, nucleoli are indistinct
  • Minimal collagen present between smooth muscle cells
  • Smooth muscle cells may resemble myofibroblasts with less cytoplasm, thinner nuclei, denser chromatin
  • Note: smooth muscle tumors of skin, vulva/vagina, scrotum, nipple and other locations are described in these chapters
Microscopic (histologic) images

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Smooth muscle

Positive stains
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