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Soft tissue
Skeletal muscle
Spindle cell variant of embryonal rhabdomyosarcoma

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 20 April 2013, last major update July 2009
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

Definition
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Epidemiology
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Case reports
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Treatment and prognosis
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Gross description
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Micro description
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Micro images
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Relatively differentiated spindle cells
Spindle cells resemble leiomyosarcoma
Spindle cells resemble MFH
Figure 1
Figure 2
Figure 3
Bladder tumor
Fig 1: somewhat bland spindle cells are characteristic
Fig 2: may be paucicellular with fibrotic stroma containing undifferentiated round and spindle cells mixed with differentiating rhabdomyoblasts with abundant eosinophilic cytoplasm
Fig 3: desmin+ rhabdomyoblasts are usually present, but often sparse

15 year old boy with paratesticular mass (Case of Week #145):
Myogenin
Desmin
Smooth muscle actin
AE1/AE3
Cytology description
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Positive stains
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Negative stains
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Differential diagnosis
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End of Soft tissue > Skeletal muscle > Spindle cell variant of embryonal rhabdomyosarcoma


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